When Lung Cancer Changes Identity: Study Maps the Immune Shift Behind Drug Resistance
A paired genomic and transcriptomic study of 32 patients shows that EGFR-mutant lung adenocarcinoma transforms into an immunosuppressed yet immunologically ...
Tag: lung adenocarcinoma
Tandem kinase TTK emerges as a master switch in lung adenocarcinoma
A bioinformatic study links the spindle checkpoint kinase TTK to poor survival and immune evasion in lung adenocarcinoma through a ...
Macrophage Signal WNT5A Drives Lung Cancer Scarring That Blocks Immunotherapy
A new study reveals how SPP1-positive macrophages secrete WNT5A to activate matrix-remodeling fibroblasts in lung adenocarcinoma, building a stiff tumor ...
AI Reads Hidden Patterns in Lung CT Scans to Tell Harmless Nodules From Invasive Cancer
A Chinese research team used CT radiomics and machine learning to distinguish harmless ground-glass lung nodules from invasive adenocarcinoma with ...
Hidden Fibroblast Subtype Drives Lung Cancer Growth and Weakens Immunotherapy
A multimodal single-cell and spatial study has uncovered a collagen-producing fibroblast subtype enriched in EGFR-mutant non-small cell lung cancer that ...
Lung Cancer Outsmarts KRAS Drugs Through Two Distinct Escape Routes
MIT researchers have found that lung adenocarcinomas can evade KRAS inhibitors either by amplifying the KRAS gene or by transforming ...
Lysosome Gene Signature Offers New Prognostic Tool for Lung Cancer
Researchers have built a 13-gene lysosome-related signature that predicts survival, immune landscape, and drug responses in lung adenocarcinoma patients.
Immunotherapy Brings Three-Year Survival in Rare, Usually Fatal Lung Vascular Cancer Syndrome
A Japanese case report describes more than three years of progression-free survival in pulmonary tumour thrombotic microangiopathy after prompt nivolumab ...
CT Growth Measurements Reveal Which Fuzzy Lung Nodules Turn Invasive
A study of 354 surgically resected subsolid lung nodules shows that CT-derived growth metrics track invasiveness across the adenocarcinoma spectrum, ...
One Dose of a New Immunotherapy Combo Triggered Four Organ Crises in a Lung Cancer Patient
A single cycle of atezolizumab plus tiragolumab triggered simultaneous myocarditis, hepatitis, thrombocytopenia, and dermatomyositis in a lung cancer patient, whose ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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