Liver Injury After CAR T-Cell Therapy May Be Driven by Cytokine Storm, Landmark Analysis Finds
A pharmacovigilance analysis of nearly five million adverse-event reports finds that liver injury after CAR T-cell therapy is predominantly early ...
Tag: liver injury
Estrogen Shields Females From Severe Hepatitis A, Mouse Study Finds
A mouse study shows that male sex hormones' absence and female estrogen signaling shape hepatitis A virus replication and liver ...
Stevia Extract Shields Diabetic Livers by Taming Iron-Driven Cell Death
A new rat study shows aqueous stevia extract protects diabetic livers by suppressing ferroptosis, boosting antioxidant enzymes, and reducing inflammation.
Scientists discover the molecular switch that lets TNF trigger cell death
A new study identifies the E3 ubiquitin ligase HERC4 as the long-sought molecular switch that licenses RIPK1 to initiate TNF-induced ...
Liver Injury in Children With Sepsis Signals Higher Death Risk, But Evidence Remains Weak
A new systematic review finds that liver injury during pediatric sepsis is associated with nearly fourfold higher odds of death, ...
Selenium Shields the Liver: Trace Element Preserves Bile Pump and Blocks Cholestatic Damage in Rats
New research shows that selenium pretreatment at 1 mg/kg protects rats from chemically induced cholestatic liver injury by preserving BSEP ...
Heat Stress Rewires Gut Microbes to Fuel Inflammation, and Arginine May Dampen the Fire
A new Microbiome study shows heat stress disrupts gut microbes to raise LPS and deplete arginine, amplifying MyD88-driven inflammation, and ...
Nanoparticle-Wrapped Herbal Compound Shields Rat Livers From Arsenic Damage
Encapsulating the kudzu-derived antioxidant puerarin in biodegradable PLGA nanoparticles protected rats from arsenic-induced liver injury by simultaneously restoring antioxidant defenses, ...
Gut Microbes Take the Wheel: How Bacterial Metabolites Remotely Steer the Liver’s Master Antioxidant Switch
A sweeping review in the Journal of Advanced Research details how gut bacterial metabolites such as butyrate, indoles, and urolithins ...
Plant Compound Bellidifolin Shields Livers From Chemotherapy Damage
A new study combining network pharmacology, molecular docking, and mouse experiments shows that the plant-derived compound bellidifolin alleviates doxorubicin-induced liver ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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