Bile Acid Receptors FXR and TGR5 Emerge as Master Switches in Liver Disease
A comprehensive new review details how the bile acid receptors FXR and TGR5 regulate fat metabolism, inflammation, fibrosis, and liver ...
A comprehensive new review details how the bile acid receptors FXR and TGR5 regulate fat metabolism, inflammation, fibrosis, and liver ...
Blocking the ghrelin receptor GHSR in infected mice suppresses host cell proliferation and strengthens fibrotic encapsulation, slowing hepatic cystic echinococcosis ...
Researchers report that loss of the K63-linked ubiquitination enzyme UBE2N in hepatocytes drives metabolic dysfunction-associated steatohepatitis by blocking p62-mediated mitophagy ...
Scientists have engineered galactose-decorated micelles that ferry the liver-protective compound marein directly into hepatocytes, markedly reducing both acute and chronic ...
A new review warns that metabolic dysfunction-associated steatotic liver disease in children is independently linked to cardiovascular risk and still ...
By combining single-cell RNA sequencing with Visium HD spatial transcriptomics, researchers have built the first spatially resolved atlas of immune ...
New research shows that individual fatty acid species differentially reprogram macrophage polarization and oxidative stress, indirectly modulating antioxidant signaling in ...
Researchers have developed a hybrid U-Net Transformer neural operator and an open-source simulation framework that significantly improves the speed and ...
A network-based study finds that the antiparasitic drug praziquantel alleviates liver fibrosis by targeting the estrogen receptor gene ESR1 in ...
Researchers have discovered that the active X chromosome in liver cells adopts a liver-specific bipartite structure whose early dissolution drives ...
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© 2025 Scienmag - Science Magazine