Type 2 diabetes fatty liver may begin in dysfunctional adipose tissue
A 2026 narrative review proposes that MASH in type 2 diabetes often begins with dysfunctional adipose tissue, which disrupts lipid ...
Tag: lipotoxicity
Body Clock Gene NPAS2 Shields the Diabetic Heart by Keeping Mitochondria Fueled
A new study shows that the circadian clock protein NPAS2 protects the diabetic heart by preserving pyruvate dehydrogenase activity and ...
Obesity from the perspective of the liver
A new review argues that obesity can be understood as a disorder of hepatic glucose and NADPH handling, in which ...
Stress Turns Brain Synapses Into Lipid Toxic Zones, New Review Warns
A new review proposes that stress-induced overactivation of phospholipase A2 deposits toxic lysophospholipids directly at brain synapses, a regional lipotoxicity ...
Fat Rewrites the Rules of Liver Cancer Across Every Disease Stage
A new review proposes that lipid metabolism plays fundamentally different roles at each stage of fatty liver disease progression to ...
Scientists Discover a Lipid-Gated Calcium Channel That Drives Diabetic Kidney Damage
A new study identifies a ceramide-gated Calhm2 calcium influx pathway, driven by Aebp1, that injures podocytes in diabetic kidney disease ...
Naked Mole Rats Park Fat in Brain Immune Cells to Shield Neurons from Aging
A comparative study finds that naked mole rats store far more fat in microglia and keep neuronal lipid droplets stable ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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