Rare POLR2A Variant Linked to Developmental Regression Shows Response to Low-Dose Dopamine Therapy
A case report describes a girl with a rare POLR2A-related neurodevelopmental disorder who showed regression and improved markedly on low-dose ...
Tag: levodopa
Rare Genetic Spastic Paraplegia Case Shows Complete Loss of Dopamine Transporter Binding on Brain SPECT
A single-case report describes a 46-year-old woman with spastic paraplegia type 7 whose FDG PET showed subtle striatal hypometabolism while ...
MRI Study Links Blood-Brain Barrier Leaks to Parkinson’s Disease
An exploratory MRI study found widespread blood-brain barrier permeability changes and altered choroid plexus contrast kinetics in patients with Parkinson's ...
Chemometric Tools Sharpen Analysis of Levodopa and Dopamine Across Complex Matrices
A new review maps how chemometric methods paired with spectroscopic, voltammetric, and chromatographic techniques are improving the simultaneous analysis of ...
Initiating levodopa pump therapy: a qualitative study of patient and caregiver perspectives
A qualitative study of 10 people with Parkinson’s disease and nine caregivers found reported symptom improvements alongside practical challenges and ...
Dopamine amplifies delayed subthalamic responses in Parkinson’s patients
Intracranial recordings from 15 people with Parkinson’s disease show that dopamine amplifies delayed subthalamic responses to cortical stimulation while leaving ...
What You Eat Could Decide How Well Parkinson’s Drugs Work
A new review in Frontiers in Nutrition reveals how dietary protein, meal timing, and gut bacteria competitively hijack levodopa transport ...
FDA Approves Juvmo, a Once-Daily Pill for Parkinson’s Born of Decades-Long D1 Receptor Research
The FDA has approved tavapadon, branded Juvmo, a once-daily D1 dopamine receptor agonist for Parkinson's disease developed from more than ...
New Dual-Release Levodopa Capsule Wins Expert Consensus for Parkinson’s Care
Nine European Parkinson's specialists have issued consensus recommendations for using the newly approved dual-release levodopa formulation IPX203 in patients with ...
Ancient Herbal Polysaccharide Turned Self-Healing Brain Gel Shows Promise Against Parkinson’s Disease
An injectable self-healing hydrogel made from an oxidized polysaccharide of the traditional Chinese medicine herb Huangjing protects dopaminergic neurons in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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