Virus-driven lymphoma cells rely on a mitochondrial enzyme duo to dodge cell death
New research reveals that the mitochondrial ubiquitin ligase MARCHF5 helps KSHV-transformed lymphoma cells survive by degrading NOXA, the natural antagonist ...
Tag: KSHV
How Cancer-Causing Viruses Hijack the Notch Signaling Pathway
A new review details how six major human oncoviruses dysregulate the Notch signaling pathway to drive proliferation, apoptosis resistance, and ...
Viral protein hijacks a metabolic enzyme to drive Kaposi’s sarcoma spread
Researchers have shown that the KSHV protein vIRF3 binds and activates the metabolic enzyme PKM2, raising acetyl-CoA levels that drive ...
Viral Gene Variant Tied to Aggressive Kaposi Sarcoma Through Inflammation
A study of 156 patients in Xinjiang, China, links a specific KSHV K15 gene variant to aggressive Kaposi sarcoma through ...
Oncogenic viruses hijack a lysosomal receptor to fuel cancer growth
A new Nature Microbiology study shows that oncogenic viruses hijack chaperone-mediated autophagy by inducing TRIM32-mediated SUMOylation of LAMP2A, promoting viral ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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