Cigarette Smoke Reprograms Lung Stem Cells, Steering Which Cancer Takes Hold
A Johns Hopkins study shows chronic cigarette smoke exposure reprograms distinct lung stem cell populations through epigenetic changes, determining whether ...
Tag: KRAS
Hypermutation Gives Weak Cancer Drivers a Head Start, Study Finds
Mathematical modelling shows that elevated mutation rates and mutational biases, rather than altered selection, can explain why weak atypical KRAS ...
Mutational Map of Gallbladder Cancer Reveals New Paths to Precision Therapy
A new review maps the recurrent mutations and signaling crosstalk driving gallbladder cancer, identifying ERBB2 and KRAS as hub targets ...
Targeting the Ubiquitin Machinery to Rewire KRAS-Driven Cancers
A new review argues that deubiquitinase enzymes within the ubiquitin-proteasome system offer promising therapeutic angles against KRAS-driven cancers that resist ...
Tree Gum Compounds Show Potent Anti-Cancer Power Against Lung Cancer Cells
Bioactive compounds from the medicinal tree Pistacia integerrima suppress the growth and migration of lung cancer cells by targeting PI3K, ...
Beyond KRAS G12C: New Drug Wave Targets Once-Undruggable Cancer Driver
A new review maps the fast-moving landscape of next-generation KRAS inhibitors, degraders, and combination strategies now advancing beyond the first ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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