Skin aging gene Foxn1 revealed as master regulator of epidermal structure and redox balance
A new BMC Biology study shows that the transcription factor Foxn1 shapes epidermal structure, collagen composition, senescence signaling, and antioxidant ...
Tag: keratinocytes
Ancient Chinese Herbal Formula Restores Skin Barrier in Eczema by Switching On a Key Repair Pathway
A clinical trial and a series of animal and cell experiments show that the traditional Chinese formula gu-ben-hua-shi repairs the ...
Cell Study Reveals How TRIM28 Fires Up Inflammatory Macrophages to Drive Keratinocyte Overgrowth
New laboratory research shows that the protein TRIM28 drives macrophages toward a pro-inflammatory state through the NLRP3/SGT1 axis and SUMOylation, ...
Umbilical Cord Stem Cell Secretome Reverses Skin Aging by Boosting Mitophagy
A cell-free secretome from human umbilical cord stem cells reverses UV-induced skin photoaging in mice and keratinocytes by restoring mitophagy ...
Vitamin D Compound Tames Psoriasis by Switching Off a Hidden Inflammatory Gene
New research reveals that calcitriol, the active form of vitamin D, suppresses psoriatic inflammation and keratinocyte hyperproliferation by downregulating the ...
Hair Follicles Mailed in a Kit Yield Stem Cells and Mini Brains
A new Nature Protocols workflow shows that keratinocytes from remotely mailed hair follicles can be reprogrammed into induced pluripotent stem ...
Mitochondria Move Between Skin Cells to Fight Sun Damage and Speed Wound Repair
Scientists show that skin cells naturally share mitochondria under ultraviolet stress and that transplanted stem-cell mitochondria can speed wound healing ...
Faulty Calcium Bridge Between Cell Powerhouses Drives Skin Barrier Breakdown in Eczema
Researchers have shown that the atopic dermatitis risk protein TMEM232 overloads the calcium bridge between the endoplasmic reticulum and mitochondria, ...
Peptide Analog Boosts Non-Viral CRISPR Delivery in Primary Human Skin Cells
Researchers engineered a cell-penetrating peptide, PF14-K, that delivers CRISPR ribonucleoproteins and DNA repair templates into primary human skin cells with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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