WSU researchers discover way to ‘crank up’ the body’s antiviral defenses
A cell-based study found that extracellular ISG15 activates a host antiviral pathway that increases epithelial-cell resistance to respiratory syncytial virus, ...
Tag: ISG15
Immune Cells That Attack the Heart: Multi-Omics Study Reveals Signature of Checkpoint Inhibitor Myocarditis
A multi-omics study identifies ISG15-positive CD8 T cells and a CCL2-CCR2-mediated inflammatory loop as drivers of immune checkpoint inhibitor-induced myocarditis, ...
Fish-Specific Ubiquitin Ligase NHRE3 Helps Virus Evade Antiviral Defenses by Degrading ISG15
Researchers identified a fish-specific E3 ubiquitin ligase, NHRE3, that suppresses antiviral immunity in grass carp and rare minnows by tagging ...
Hidden Protein Bosses the Cleanup Crew That Keeps Lupus at Bay
Scientists have discovered that the protein FAM76B regulates macrophage clearance of dying cells through an m6A-ISG15-autophagy pathway whose failure drives ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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