Chemists Craft a One-Handed Molecule That Disarms a Cell-Death Protein
Chemists have developed a single-enantiomer covalent inhibitor that locks the cell-death protein BAX in its inactive state and protects tissue ...
Tag: ischemia reperfusion injury
Exercise Rewires Heart Metabolism Through a Single NADPH-Producing Pathway
A new Nature Metabolism study shows that exercise boosts cytosolic NADPH via the pentose phosphate pathway, driving healthy heart growth ...
Cytosolic NADPH Emerges as the Molecular Signal That Lets the Heart Mimic Exercise
New research in Nature Metabolism shows that raising cytosolic NADPH, a pentose phosphate pathway metabolite, recreates the heart-protective effects of ...
Warming Donor Organs to 10 Degrees Celsius May Outperform Traditional Ice Storage
A new narrative review finds that storing donor organs at 10 degrees Celsius instead of on ice may preserve mitochondrial ...
Damaged lysosomes undergo budding-type fission driven by mitochondrial vesicles
In a discovery that reshapes how biologists think about cellular quality control, researchers have identified an entirely new mechanism by ...
Macrophage Adenylyl Cyclase 7 Shields Male Mice From Ischemia-Reperfusion Injury
A new study from Nature Communications highlights an unexpected immune target in the heart’s response to injury. Researchers report that ...
Dopamine D2 Receptors and Heart Cell Death Unveiled
In a significant development within the biomedical research community, the article titled "Role of dopamine D2 receptors in ischemia/reperfusion induced ...
Neural Progenitor Cell Exosomes Aid Ischemia/Reperfusion Recovery
Recent research has spotlighted the significant role of cell communication in mediating various physiological and pathological processes. A pivotal study ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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