Astragaloside IV Emerges as a Candidate Ferroptosis Link in Heart Hypertrophy
Astragaloside IV reduces pathological cardiac hypertrophy and suppresses ferroptosis in separate models, but direct experiments are needed to establish whether ...
Tag: iron metabolism
Mitochondria emerge as the central hub linking cell death and metabolism in gum disease
A new review proposes that mitochondrial collapse drives a self-reinforcing cycle linking ferroptosis and metabolic reprogramming in periodontitis, opening the ...
How a Cellular Fuel Sensor Helps Red Blood Cells Survive Anemia
A new study reveals how the energy sensor AMPK stabilizes the oxygen-responsive protein HIF-2α to drive red blood cell maturation ...
Iron, Inflammation, and a Deadly Paradox: Rethinking Cancer Wasting Through Ferroptosis
A new iScience review argues that ferroptosis, an iron-driven form of cell death, links tumor and immune signals to muscle ...
Scientists Map the Iron Recycling Switch That Decides Whether Cells Live or Die
A new review in the Journal of Translational Medicine maps how NCOA4-mediated ferritinophagy controls iron release and ferroptosis, cataloguing small-molecule ...
Iron and Methionine Metabolism Drive Fat Browning in Cancer Cachexia
A new Nature Cancer study identifies an iron-regulated methionine oxidation pathway and the repair enzyme MSRA as drivers of adipose ...
Chemical Maps Expose Iron-Linked Enzyme as Hidden Guardian of Damaged DNA
A comprehensive chemogenomic map of the DNA damage response reveals that peroxiredoxin 1 safeguards cells against iron-driven oxidative DNA damage.
Copper and Iron Cell Death Pathways Offer a New Two-Front Attack on Liver Cancer
A new review in Medical Oncology argues that simultaneously targeting copper-triggered cuproptosis and iron-dependent ferroptosis could open a powerful two-front ...
Targeted Gene Sequencing Transforms Molecular Diagnosis of Hereditary Hemochromatosis
A Greek study shows that targeted next-generation sequencing combined with structural protein modeling improves the molecular diagnosis of hereditary hemochromatosis.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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