Tag: intervertebral disc degeneration

A new study shows that the rare sugar D-allose restores mitophagy, suppresses cGAS–STING signalling and preserves the cytoprotective peptide ADM2 ...

New research in mice shows that age-related loss of Wnt signaling in intervertebral disc cells suppresses chemokine production and blunts ...

Rapamycin-loaded nanoliposomes inhibited mTORC1-driven senescence in rat disc cells and slowed intervertebral disc degeneration in vivo, pointing toward an injectable ...

A classical Chinese herbal formula, Juanbi Tang, attenuates intervertebral disc degeneration in rats by suppressing p38MAPK/NF-κB signaling, activating Atg5-dependent autophagy, ...

New research shows that the epigenetic enzyme HDAC1 preserves metabolic balance in nucleus pulposus cells through post-translational modification interactions with ...

Low back pain may be common, but one of its most stubborn biological causes is hidden deep inside the spine: ...

A groundbreaking study published in the September 2025 issue of Aging-US has unveiled a pivotal role of the transcription factor ...

In a pioneering study published recently in Nature Communications, researchers have unveiled a novel epigenetic mechanism that could revolutionize our ...

In a groundbreaking study published recently in Cell Death Discovery, researchers have unveiled a novel molecular mechanism that accelerates the ...

Recent advances in cellular and molecular biology have unveiled critical insights into the mechanisms underlying intervertebral disc degeneration (IDD), a ...