Liver Survival Protein USP18 Protects Cells From Proteotoxic Stress
A study in mice and liver cells finds that the USP18–STAT2 axis, activated by interferon priming, protects hepatocytes from proteasome-inhibitor-induced ...
Tag: interferon-stimulated genes
Progenitor cells dominate antiviral gene responses to Zika in fetal neural tissue
A secondary analysis of single-cell data finds that progenitor-enriched radial glia-like cells and cycling neural progenitor cells show the strongest ...
MARK3 kinase drives antiviral defense through GEF-H1 and TBK1 signaling
A new study identifies MARK3 as a kinase that promotes type I interferon production by phosphorylating GEF-H1 and activating the ...
Antiviral Protein IFIT1 Emerges as a Driver of Lupus Progression
New research shows that the antiviral protein IFIT1 is elevated in immune cells of lupus patients, where it promotes cell ...
Gut Microbes From Elderly Humans Weaken Intestinal Barriers When Transplanted Into Pigs
A new pig model study shows that fecal microbiota from elderly human donors, compared with microbiota from young adults, reshapes ...
GALNT2 Gene Limits Respiratory Virus Infections
In a groundbreaking discovery that could revolutionize the fight against respiratory viral infections, researchers have identified a crucial role for ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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