Tag: inhibitor

Peripheral nerves lose much of their ability to repair themselves as bodies age, and a new comparative genomics study points ...

A new narrative review maps the rare but potentially fatal cardiovascular toxicities of immune checkpoint inhibitors, from fulminant myocarditis to ...

For more than two decades, one small molecule has quietly underpinned nearly every effort to sabotage the molecular garbage disposal ...

A selective RIPK1 inhibitor prevented hypotension, tachycardia, and inflammatory damage in a rat hind limb ischemia/reperfusion model by suppressing necroptotic ...

Hepatocellular carcinoma, the most common form of primary liver cancer, remains one of the deadliest malignancies worldwide, with prognosis poor ...

A new review maps how aggressive cutaneous T-cell lymphomas develop resistance to targeted kinase inhibitors, revealing gatekeeper mutations and cross-kinase ...

Immune checkpoint inhibitors have transformed the outlook for many patients with advanced cancer, but the same immune reawakening that lets ...

A computational study identified fibroblast activation protein as the top stromal target in rectal cancer and designed a peptide inhibitor ...

Two decades of relentless pharmacological innovation have transformed HIV from a uniformly fatal diagnosis into a manageable chronic infection for ...