Artemisinin May Curb Gastric Cancer Cells by Damping ERK Signaling
A new in vitro study reports that artemisinin suppresses gastric cancer cell proliferation, migration, and invasion while reducing ERK/MAPK pathway ...
Tag: in vitro
Novel Benin phages show broad lytic reach against drug-resistant Klebsiella
Researchers isolated three new Klebsiella phages from Benin that lyse multidrug-resistant and hypervirulent strains across many capsular types and disrupt ...
NU7441 shows dual BRD4 and DNA-PK activity in ovarian cancer cells
Preclinical assays found that NU7441 displaced BRD4 from acetylated chromatin and impaired homologous recombination and non-homologous end joining in ovarian ...
Fatty Acid Additive With Dexamethasone Curbs Inflammatory Signal in Cell Model
Decanoic acid, a saturated medium-chain fatty acid, suppressed the release of the proinflammatory cytokine interleukin-1β in a laboratory model of ...
Synthetic Peptide IL15.3 Calms Inflamed Immune Cells on Multiple Fronts
The synthetic antimicrobial peptide IL15.3 reduced inflammatory signaling in LPS-stimulated macrophages through coordinated transcriptional and proteomic changes, with low cytotoxicity ...
Virtual screening yields two drug candidates that disable c-Myc in colorectal cancer
A multi-stage virtual screening campaign against the c-Myc/Max dimerization interface has identified two small molecules that suppress c-Myc protein, block ...
Chemically linked phage endolysins broaden and strengthen in vitro bacterial killing
Chemically conjugating antimicrobial peptides to the phage-derived endolysin LysJEP8 strengthened in vitro killing of Acinetobacter baumannii and extended activity to ...
Thai Yoom Noon Rice Extracts Show Anti-Cancer and DNA-Protective Effects in Lab Tests
Laboratory tests show that extracts of Thailand's flavonoid-rich Yoom Noon rice kill colorectal cancer cells, block their migration, and protect ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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