Nasal influenza antivirals advance as researchers map models to cut animal testing
A new review maps infection models and regulatory pathways for developing anti-influenza nasal sprays while reducing animal testing.
Tag: in vitro models
Lab Barrier Models Show Serum Protein Binding Shapes Antiviral Entry into the Brain
A human cell-based in vitro study reports that highly protein-bound antivirals such as dolutegravir and efavirenz show reduced permeability across ...
Adult ADHD-linked PARK2 variants subtly reshape lab-grown blood-brain barrier cells
Lab-grown blood-brain barrier cells from adults with ADHD carrying PARK2 copy number variations show small genotype-linked changes, while culture duration ...
Why the Gut Microbiota Refuses to Behave in a Jar: The Hidden Science of Building a Fake Gut
A new review argues that building a faithful fake gut depends less on sophisticated bioreactors than on mastering the humble ...
Why a Single EC50 Cannot Capture the True Power of an Antiviral Drug
A new review argues that conventional EC50 and EC90 values are context-dependent dynamic phenotypes shaped by viral kinetics, host-cell biology, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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