Tag: Immunotherapy Resistance

A phase II pilot trial found that a single fecal microbiota transplantation combined with atezolizumab and bevacizumab was safe and ...

Plasma-derived small extracellular vesicles from head and neck cancer patients suppress T-cell proliferation, trigger apoptosis, and rewire immune checkpoint expression ...

A new review in Molecular Cancer explains how tumor-derived exosomes act as mobile signaling hubs that spread immune suppression, drive ...

A new review in Medical Oncology maps how the tumor microenvironment and gut microbiome drive resistance to immune checkpoint inhibitors ...

New research reveals that the tumor protein CEMIP drives extracellular vesicle output, reprograms macrophages by disrupting HSP90-JAK2 signaling, and enables ...

New research links the gene GNG4 in malignant liver cells to tumor immune exclusion and reduced CD8-positive T cell infiltration ...

A new review in the Journal of Translational Medicine details how mitochondrial metabolic reprogramming in tumor cells drives immune evasion ...

Researchers engineered an anti-C4d antibody that targets complement fragments left on tumor cells that survived antibody therapy, boosting complement-mediated killing ...

A new review in Medical Oncology synthesises evidence that tumours form functional synapses with neurons and exploit autonomic signalling to ...

A new review details how microbial imbalances in the gut, airways, mouth, and tumors drive lung cancer progression and undermine ...