Navigating metabolomics in the era of immunometabolism
A review in translational medicine outlines how immunologists can design metabolomics experiments and interpret nutrient-tracing data to investigate metabolic regulation ...
Tag: immunology
Modified antibodies curb neutrophil surge in early autoimmune kidney disease
University of Osaka researchers mapped the earliest cellular events of ANCA-associated glomerulonephritis and showed that modified antibodies reducing Fcγ receptor ...
Single-Cell Atlas Reveals How a Rare ANO5 Mutation Dismantles Muscle From Within
The first single-cell RNA sequencing study of an LGMD R12 patient reveals stalled muscle regeneration, metabolic collapse, and activated immune ...
Tocilizumab Rechallenge at Reduced Dose Still Triggers Fibrinogen Crash in Arthritis Patient
A case report shows tocilizumab-induced hypofibrinogenemia recurred in a rheumatoid arthritis patient even after the drug dose was substantially reduced.
Mitochondrial quality control genes CDC42 and RBBP7 emerge as key players in rheumatoid arthritis
A new study integrating bulk and single-cell RNA sequencing identifies two mitochondrial quality control-related genes with distinct immune and metabolic ...
Zebrafish Take Center Stage as Scientists Redefine the Future of Preclinical Research
The Polish Zebrafish Society has issued comprehensive national recommendations positioning the zebrafish as a rigorous, ethical, and faster alternative to ...
Machine learning pinpoints CXCL13 and CXCL10 as diagnostic biomarkers for rheumatoid arthritis
A machine learning study of synovial tissue transcriptomics identifies the chemokine genes CXCL13 and CXCL10 as promising diagnostic biomarkers for ...
Cholesterol Carriers in the Blood Reveal Which Cirrhosis Patients Will Develop Infections
A cohort study of 311 patients with cirrhosis finds that low HDL cholesterol and apolipoprotein A-I predict infection risk within ...
Tildrakizumab Shows Sustained Real-World Benefit in Japanese Psoriasis Patients Over 52 Weeks
A 52-week Japanese observational study found that tildrakizumab sustained meaningful disease control in real-world psoriasis patients, with 60 percent achieving ...
When Lupus Masks the Lab: Why a Single Complement Test Can Mislead Angioedema Diagnosis
A Japanese family case report shows that profoundly low C1q, usually a hallmark of acquired angioedema, can instead reflect lupus-related ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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