Semi-Automated Pipeline Counts Muscle Fiber Nuclei and Satellite Cells at Scale
Researchers have validated a semi-automated image analysis pipeline that quantifies Pax7+ satellite cells, myonuclei, cross-sectional area, perimeter, and fiber type ...
Tag: immunohistochemistry
Psoriasis Study Finds Key Anti-Angiogenic Protein Depleted in Lesional Skin
A new cross-sectional study finds that the anti-angiogenic protein PEDF is markedly depleted in psoriatic lesional skin but unchanged in ...
Rare Ovarian Tumor Defies Expectations With Unusual Hormone Receptor Signature
A new case report documents an ovarian microcystic stromal tumor with unusual androgen receptor and partial S100 expression, expanding the ...
Brain Water Channels May Finally Help Forensics Tell Freshwater From Saltwater Drowning
A new forensic study shows that freshwater drowning triggers significantly stronger cerebral expression of aquaporin 4 and aquaporin 9 than ...
STING and p53 Rise in HPV-Linked Skin Cancers, Landmark Study Finds
Researchers in São Paulo report that skin cancers arising in patients with epidermodysplasia verruciformis show markedly higher STING and p53 ...
Ovarian Cancer Returns as a Rare Breast Tumor in a Puzzling Case
A striking case report describes how a borderline ovarian tumor with negative lymph nodes returned as high-grade metastases in a ...
Hidden Fibroblast Signal Reveals Endometriosis Lesions Invisible to Standard Imaging
A Mayo Clinic study shows that deep and superficial endometriosis lesions both express fibroblast activation protein, including lesions poorly visible ...
Dual PI3K/mTOR Inhibitor VDC597 Shows Promise Against Canine Lymphoma and Leukemia in Lab Studies
A dual PI3K/mTOR inhibitor, VDC597, suppresses signaling, kills canine lymphoma and leukemia cells in vitro, and synergizes with dexamethasone, according ...
Hidden Mesothelioma Masqueraded as Tuberculosis Until a Rapid Chest Tumor Appeared
A new case report describes how an aggressive sarcomatoid mesothelioma hid behind a convincing picture of tuberculous pleurisy for months, ...
Rare Muscle-Infiltrating T-Cell Lymphoma in a Dog Challenges Diagnosis
Veterinarians at Colorado State University report a rare case of canine T-cell lymphoma with extensive skeletal muscle involvement and aberrant ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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