HLA variants linked to pediatric neuroblastoma risk and outcomes in review
A 2026 narrative review links inherited HLA class I and class II variation to pediatric neuroblastoma susceptibility and selected outcomes, ...
Tag: immunogenetics
Genes and Immune History May Shape Dengue and Zika Risk as Climate Warms
A new Perspective argues that host genetics, HLA diversity, and immune history must be integrated with climate models to predict ...
Argentina Builds Its Own Transplant Matching Calculator to Reflect Local Donors
Researchers in Argentina have developed cPRArgentina, a web-based calculator that estimates transplant donor incompatibility using local deceased donor data and ...
Immune Genes Shape How a Transplant Menace Is Seen in Peru
A Peruvian study of 562 kidney transplant candidates maps how local HLA diversity changes which cytomegalovirus epitopes the immune system ...
Rare Immune Genes Point to Autoimmunity in Bladder Pain Syndrome
High-resolution HLA sequencing reveals rare immune alleles significantly enriched in patients with Hunner type interstitial cystitis, providing genetic evidence for ...
Family-Phased HLA Haplotype Database Goes Online for Brazilian Transplant Medicine
GERBase offers freely queryable, family-phased high-resolution HLA allele and haplotype frequencies with linkage disequilibrium metrics from 17,260 Brazilian transplant candidates, ...
Hidden Immune Gene Variant May Explain Dangerous Blood Transfusion Reactions in Thalassemia Patients
For patients with transfusion-dependent thalassemia, a lifetime of regular blood transfusions is both a lifeline and a immunological tightrope walk. ...
Immune Gene Profiles Linked to Higher EBV DNA Levels in Nasopharyngeal Cancer
A case-control study in southern China links the HLA-A*11:01-negative/KIR2DS4 Deleted/Deleted immune gene profile to significantly higher pretreatment plasma Epstein-Barr virus ...
Obesity Accelerates MS Disability Only in People Lacking a Key Immune Gene, Swedish Study Finds
A Swedish study of 2,117 people with multiple sclerosis found that obesity at diagnosis accelerates long-term disability progression almost exclusively ...
T-Cell Activation State Reshapes Asthma Genetics and Points to New Drug Targets
A large genetic analysis shows that asthma-linked gene regulation in CD4+ T cells changes with activation state, exposing dozens of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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