Tag: immune checkpoint inhibitors

Researchers at the University of Bern show that the miR105/767 microRNA cluster coordinates apoptosis, cell-cycle progression, and PD-L1 expression in ...

A new transcriptomic study reveals that biological sex shapes how regulatory T cells reprogram during checkpoint inhibitor toxicities and autoimmune ...

Researchers found that inhibiting the RNA editing enzyme ADAR1 reprograms the immunosuppressive tumor microenvironment of bladder cancer and sensitizes it ...

A network meta-analysis of eight Phase III trials involving 7,127 patients suggests that the PD-1/CTLA-4 bispecific antibody cadonilimab plus chemotherapy ...

A selective dual T-cell activator directed at the TCR beta chain revives exhausted antitumor T cells and sensitizes checkpoint-resistant cancers ...

A systematic review of 116 case reports reveals that immune checkpoint inhibitors can trigger rare but often fatal heart complications, ...

A new review in the Journal of Translational Medicine synthesizes a decade of evidence showing that liquid biopsy analytes such ...

A retrospective study of 195 colorectal cancer patients found that removing twenty or more tumor-draining lymph nodes after neoadjuvant immunotherapy ...

A translational modelling study finds that PD-1 receptor occupancy does not predict immune activation during pembrolizumab therapy, challenging current dosing ...

A new commentary warns that the three-factor risk model proposed for esophageal cancer patients achieving pathological complete response after neoadjuvant ...