Tag: immune checkpoint inhibitors

A new review argues that gut bacterial metabolites such as butyrate and indoles can be engineered as programmable drugs to ...

A new study links tumor-derived TNF-α, CCL4-high tumor-associated neutrophils, and suppressed T-cell activity to immunotherapy resistance in non-small cell lung ...

A new review finds checkpoint inhibitors are safe and effective for virologically suppressed people with HIV, while sub-Saharan Africa remains ...

A new review examines how patient-derived tumor organoids retaining immune cells could improve preclinical prediction of immunotherapy response while noting ...

A new review details how engineered oncolytic viruses selectively kill tumors, ignite antitumor immunity, and where clinical translation still falls ...

A new review finds that combining immune-checkpoint inhibitors with locoregional therapies improves progression-free survival in hepatocellular carcinoma, but overall survival ...

A new study reports that the RNA m5C methyltransferase NSUN2 suppresses CCL5-driven CD8+ T cell recruitment in lung adenocarcinoma through ...

Organoid and clinical single-cell data link a DHX58-positive, CD62L-positive stem-like T-cell state to immune checkpoint blockade responsiveness in gastric cancer.

A systematic review proposes a clinically actionable biomarker stratification for immunotherapy in microsatellite-stable colorectal cancer, where response rates to checkpoint ...

A multi-phase Nature Cancer study found that an agentic AI system detected immune-related adverse events in clinical notes with retrospective ...