Turning Cold Tumors Hot: Dual-Target Therapy Offers New Hope for Platinum-Resistant Ovarian Cancer
A new review outlines how combining PARP inhibitors with immune checkpoint inhibitors can convert immunologically cold ovarian tumors into hot ...
Tag: immune checkpoint inhibitors
Immune Cells Cluster, Not Crowd, in Melanoma That Spreads to the Brain
A Dutch study finds that melanoma brain metastases harbor far fewer but more tightly clustered immune cells than other metastases, ...
Ranking the Safest Immunotherapy-Chemo Combos: Massive Analysis of 36,664 Cancer Patients Reveals Clear Winners
A network meta-analysis of 58 phase III trials covering 36,664 patients ranks the safety of 20 immune checkpoint inhibitors combined ...
How Stomach Bacteria Rewire Immune Checkpoints to Fuel Gastric Cancer
A new review explains how Helicobacter pylori virulence factors drive PD-L1 expression in gastric cancer through crosstalk among the NF-κB, ...
Epigenetic Boost Fails to Awaken Immune Therapy in Bile Duct Cancer Trial
A phase 2 trial found that the HDAC inhibitor entinostat combined with nivolumab produced no tumor responses in advanced cholangiocarcinoma, ...
Morning infusions may boost immunotherapy survival benefit, major analysis finds
A new meta-analysis of nearly 12,000 patients links early-day immune checkpoint inhibitor infusions with markedly better survival in advanced solid ...
Stem Cells and Exosomes Offer Hope for Kidneys Damaged by Cancer Therapy
A new review in Holistic Integrative Oncology details how mesenchymal stem cells, renal progenitor cells, and exosomes could protect cancer ...
Melanoma’s Genetic Blueprint Builds Immune-Proof Tumor Neighborhoods, Study Finds
Researchers at NYU Grossman School of Medicine show that loss of the NF1 tumor suppressor reorganizes melanoma tumors into immunosuppressive ...
CD58 Emerges as a Central Player in How Tumors Evade Immune Attack and Resist Therapy
A new review in Molecular Cancer details how loss of the immune synapse molecule CD58 drives tumor immune evasion and ...
Hidden Statistical Bias May Have Inflated Immunotherapy Hopes in Mesothelioma Trial
A new analysis shows that post-progression censoring may have generated a misleading survival advantage for nivolumab in second-line mesothelioma, resolving ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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