Circadian Clock Loss May Amplify Growth Hormone Signaling in the Heart
A minireview reports that cardiomyocyte-specific loss of the Bmal1 clock gene increases cardiac growth hormone sensitivity in mice, raising a ...
Tag: IGF-1
Research report: Editorial: Growth and pubertal development in paediatric endocrinology: from physiological pathways to clinical challenges
A paediatric endocrinology research collection links growth and pubertal development with genetic, environmental, metabolic and cardiac findings while emphasizing the ...
Interpretable machine learning identifies predictors of IGF-1 during growth hormone therapy in boys
Interpretable machine learning models applied to a Swedish clinical trial cohort of 72 boys receiving growth hormone therapy identified current ...
Cancer’s resistance may be written years before treatment begins, new hypothesis argues
A new hypothesis proposes that chronic metabolic dysregulation epigenetically primes apoptosis-resistant cancer clones years before diagnosis, reframing treatment resistance as ...
Fasting Hits Laying Hens Harder Than Fiber Diets, Revealing How Molting Rewires Hormones and Metabolism
A controlled trial in Rhode Island Red hens shows that the severity of endocrine and metabolic disruption during induced molting ...
Statin-Triggered Liver Aging May Quiet IGF-1 Signals and Shrink Muscle, Study Finds
New research in Cell Death Discovery shows that statins can induce senescence in liver cells, reducing circulating IGF-1 and triggering ...
Skin Deep No More: Vitiligo Doubles the Risk of Metabolic Syndrome and Insulin Resistance
A systematic review of 33 studies covering 4,286 patients finds that people with vitiligo show roughly double the prevalence of ...
Deer Antler Velvet Draws Scientific Scrutiny as Regenerative Super-Ingredient
A new comprehensive review finds that deer antler velvet is packed with growth factors and bioactive compounds, but warns that ...
Fatty Liver Disease Linked to Growth Hormone Disruption in Children with Type 1 Diabetes
A new study of 250 children with type 1 diabetes finds that fatty liver disease and reduced IGF-1 levels are ...
Lymphatic Vessels Emerge as Hidden Conductors of the Developing Heart’s Growth
Northwestern scientists have discovered that cardiac lymphatic vessels secrete the protein Reelin to maintain the epicardium and fibroblasts, revealing a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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