Diseased Blood Vessels May Drive Fibrosis Across Multiple Organs
A new review argues that dysfunctional blood vessels, through failed endothelial quiescence, abnormal remodeling modes and disrupted angiocrine signaling, may ...
Tag: hypoxia
Why Oxygen Uptake Collapses at Altitude: Diffusion, Not the Heart, Emerges as the Main Barrier
A new physiological analysis argues that oxygen diffusion limits in the lungs and muscles, rather than reduced cardiac output or ...
Hypoxia-induced GP73 promotes the Warburg effect in hepatocellular carcinoma via HIF-1α
A cell and patient-cohort study links hypoxia-induced GP73 to HIF-1α-dependent glycolysis, growth, invasion and markers of transarterial chemoembolization resistance in ...
Adult lung study finds no diffuse fibrosis in Alström syndrome
A retrospective study of 46 adults with Alström syndrome found no diffuse pulmonary fibrosis on HRCT scans or post-mortem tissue, ...
Breast Cancer Drug Lapatinib Shows Modest Boost to Ultrasound Therapy in Prostate Cancer Cells
A laboratory study finds that the approved kinase inhibitor lapatinib can improve retention of a nanoparticle sonosensitizer in hypoxic prostate ...
Baltic Sea Sediments Lose Their Power to Trap Sulfide as Hypoxia Persists
A 15-month Baltic Sea study found that recurring oxygen depletion progressively exhausts the sediment's capacity to retain sulfide, creating feedbacks ...
High-altitude exposure linked to α-synuclein burden and mouse pathology
A multi-method study linked chronic high-altitude exposure to elevated α-synuclein levels and worse pathology in a mouse model, while human ...
Review outlines chemotherapy-related fatigue in breast cancer patients at high altitude
A review identifies inflammation and immune readjustment as central factors in chemotherapy-related fatigue among breast cancer patients, while noting that ...
Machine learning and cell study link shikonin to Parkin-dependent activity in hypoxic triple-negative breast cancer
A machine-learning and cell-culture study found that shikonin induced necroptosis and apoptosis in hypoxic MDA-MB-231 breast cancer cells through a ...
Case report of lip protrusions in three trahira found in a drying Brazilian pool
A case-study report of six trahira from Brazilian temporary pools found lip protuberances in three fish from a low-oxygen drying ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!