Astrocytes Emerge as Central Players in the Deadly Chain Linking Seizures to Breathing Failure
A new review argues that astrocytes, not just neurons, play a pivotal role in the respiratory failure and brainstem dysfunction ...
Tag: hypoxia
How Toxic Cyanobacteria Take Over Estuaries: Nutrient Imbalance and Warming Explained
A new review explains how nitrogen-fixing, buoyancy-regulating cyanobacteria exploit low N:P ratios and thermal stratification to displace eukaryotic algae in ...
Mississippi’s Fertilizer Flood Feeds the Gulf of Mexico’s Colossal Dead Zone
A new review traces how more than a century of synthetic fertilizer use across the Mississippi River Basin drives the ...
How Low Oxygen Helps Neuroblastoma Turn Killer T Cells Off
New research shows that oxygen-starved neuroblastoma cells stabilize HIF-1α, which directly activates PD-L1 transcription and drives CD8+ T-cell dysfunction, a ...
3D Tumor Models Expose How Biliary Tract Cancers Evade Chemotherapy
A new review argues that three-dimensional tumor models, including patient-derived organoids, can reveal the drug resistance and apoptosis evasion mechanisms ...
Low Oxygen Helps Early Embryos Switch On Their Genes, Mouse Study Finds
A new mouse study shows that hypoxic culture enhances zygotic genome activation by increasing H3K4me3 at zygotic gene promoters and ...
Proteomic Map of Sickle Cell Retinopathy Reveals Early Photoreceptor Breakdown in Humanized Mice
The first comprehensive proteomic analysis of retinas from humanized sickle cell anemia mice reveals early downregulation of phototransduction and mitochondrial ...
Oxygen Shapes the Developing Cortex, but HIF-2α Turns Out Not to Be the Messenger
A new mouse study shows that oxygen levels strongly influence cortical development, but the oxygen sensor HIF-2α is not the ...
Single Gene Emerges as Hidden Link Between Oxygen Starvation and Neuron Death in Parkinson’s Disease
A multi-omics study identifies the mitochondrial pyruvate carrier gene MPC2 as a causal link between hypoxia, mitochondrial energy failure, and ...
Immune Checkpoint Blockers and Engineered Cells Reshape the Fight Against Oral Cavity Cancer
A new review in Molecular Biology Reports maps how checkpoint inhibitors, engineered cell therapies, and emerging immunotherapies are transforming treatment ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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