Tag: humanized mouse models

A review challenges the classical mononuclear phagocyte system model, proposing that macrophages act as mobile messengers and evaluating humanized mouse ...

Engineered renal cancer assembloids reveal a tumour–fibroblast–T cell signalling axis that governs stem-like CD8+ T cell maintenance and heterogeneous responses ...

Using patient-derived hepatocellular carcinoma organoids, researchers identified mITGB2, a splice-variant-derived peptide presented by MHC class II, as a functionally immunogenic ...