Bdelloid rotifers repair chromosomes across generations
A peer-reviewed study in the asexual bdelloid rotifer Adineta vaga shows how fragmented chromosomes can be retained across generations and ...
Tag: homologous recombination
Genome-wide analysis links tumor deletion patterns to alternative DNA repair
A whole-genome analysis of 2,157 tumors across 17 cancer types identified distinct deletion patterns associated with two backup DNA-repair pathways, ...
Agrobacterium’s Own T-DNA Powers Simple One-Step Genome Editing
Chinese researchers have developed a one-step genome editing method for Agrobacterium that uses the bacterium's own induced T-DNA as a ...
Two-Drug Strike Cripples DNA Repair in Malaria Parasite
New research shows that inhibiting the chaperone PfHsp90 with 17-AAG destabilizes the malaria parasite's Bloom helicase PfBlm and potentiates the ...
DNA Repair Enzyme Pol ι Emerges as Key Player in Early Breast Cancer Risk in BRCA2 Carriers
A new iScience study shows that the error-prone polymerase Pol ι is induced in BRCA2-deficient mammary epithelial cells, where it ...
DNA Repair Enzymes RecA and UvrD Emerge as Central Players in Antibiotic Persister Survival
New genetic analysis in Escherichia coli reveals that the DNA repair hub proteins RecA and UvrD are essential for fluoroquinolone ...
Baltic Sea Sediments Drive Surprising Sexual Speciation in Bacteria
Genomic analysis of Shewanella baltica strains from Baltic Sea sediments reveals that recombination-driven, or sexual, speciation can produce distinct bacterial ...
Epigenetic enzyme SMYD3 emerges as Achilles heel of gastric cancer DNA repair
New research reveals that the chromatin-modifying enzyme SMYD3 orchestrates DNA double-strand break repair in gastric cancer, and that blocking it ...
How Cells Choose Between DNA Repair Pathways—and Why It Matters for Cancer
A new review explains how the contest between BRCA1-BARD1 and the 53BP1 axis at DNA break ends determines whether cells ...
CRISPR Screen Reveals DNA Repair Machinery as Achilles Heel for Antibiotic Boosting
A genome-wide CRISPR interference screen has identified the conserved bacterial homologous recombination pathway, and the RecA protein in particular, as ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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