Tag: histone modifications

Scientists discovered that the chromatin remodeler BRG1 drives diabetic corneal neuropathy in mice by activating PI3K/AKT signaling to fuel excessive ...

A scientific review details how epigenetic mechanisms influence complement system activity and tissue vulnerability across context-dependent stages of biological aging.

An analysis of placental tissue from 60 patients linked gestational SARS-CoV-2 exposure to reduced syncytiotrophoblast H3K4me3 histone modifications without altering ...

A systematic review of nine preclinical rodent studies reveals that dietary restriction attenuates age-related brain epigenetic drift and supports cognitive ...

Four coordinated single-cell studies published in Cell examine how distinct brain cell identities and gene regulatory programs are established and ...

Researchers integrated single-cell gene expression and histone modifications to map chromatin states across more than 100 cell subclasses in the ...

Researchers with the BRAIN Initiative have constructed a multimodal single-cell atlas mapping cellular diversity and epigenetic architecture across the human ...

A scientific review details how lactate metabolism drives cancer epigenetic remodeling, influencing DNA methylation, histone lactylation, RNA modifications, and chromatin ...

Researchers have developed a blood-testing approach that analyzes circulating chromatin fragments to monitor tumor burden and identify molecular subtypes in ...

Researchers discovered that water flea embryos alter histone H3 lysine 9 acetylation and methylation patterns to coordinate developmental arrest and ...