Scientists Map the Earliest Steps of Polycomb Gene Silencing in Human Embryos
A Nature Genetics study shows that the histone mark H2Aub laid down by PRC1 guides the reestablishment of Polycomb repression, ...
Tag: histone modification
Epigenetics and Metabolism: The Two-Way Conversation Driving Liver Cancer
A new review in the Chinese Medical Journal maps how epigenetic modifications and metabolic reprogramming fuel each other in hepatocellular ...
New Database Maps How 653 Food Compounds Rewire Our Epigenome
A new AI-curated database links 653 dietary compounds to 80 epigenetic targets across nearly 2,000 studies, creating the most comprehensive ...
Innate Immune Memory: How Epigenetic and Metabolic Rewiring Shapes Health and Disease
A new review in the Journal of Molecular Medicine explains how trained immunity, driven by epigenetic and metabolic reprogramming of ...
High Blood Sugar Rewrites Pancreatic Cell Chemistry, Driving Stress Granule Buildup in Diabetes
New research shows that diabetes elevates the histone mark H3K4me1 in pancreatic acinar cells, driving stress granule formation under high ...
Genes and Epigenetics Converge to Explain Sudden Cardiac Death Without Family History
A new review maps how common genetic variants, insertion/deletion polymorphisms, microRNAs, DNA methylation and histone modifications together shape the risk ...
Lactate’s Hidden Switch: How a Once-Dismissed Metabolite Shapes Brain Repair and Degeneration
A new review in the Journal of Translational Medicine details how lactate and protein lactylation act as a double-edged sword, ...
Zebrafish Reveal How Polycomb Complexes Sculpt the Heart and Fins
A new review shows that Polycomb repressive complexes PRC1 and PRC2 are essential for zebrafish heart looping, contraction and pectoral ...
How Plant Polyphenols May Rewrite the Epigenetic Damage That Drives Cancer
A new review details how reactive oxygen species drive cancer through reversible epigenetic damage and how dietary polyphenols such as ...
How Plants Rewind Their Cells: The Molecular Secrets of De Novo Organogenesis
A new review maps how hormones, gene networks, and epigenetic marks allow mature plant cells to revert to a pluripotent ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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