How Much Sequencing Is Enough? Study Maps the Depth Limits of Hi-C Chromatin Maps
A systematic subsampling analysis of twelve Hi-C libraries reveals that different chromatin metrics need vastly different sequencing depths, with genome-average ...
A systematic subsampling analysis of twelve Hi-C libraries reveals that different chromatin metrics need vastly different sequencing depths, with genome-average ...
Researchers have assembled the first telomere-to-telomere, gap-free genome of the Chinese holly, resolving its chromosome number and revealing duplications that ...
A massive Hi-C study across eight mouse strains shows that the strength of chromatin boundary insulation predicts how faithfully topologically ...
Scientists harnessed piggyBac transposon mapping and Hi-C chromatin analysis in Penicillium rubens to identify expression hotspots that boosted production of ...
The first Hi-C analysis of the tiny alga Ostreococcus tauri shows that its enigmatic low-GC outlier chromosomes fold into sharply ...
A massive multi-omics atlas of pig skeletal muscle shows how genetically regulated DNA methylation links sequence variation to gene expression ...
New research shows that African swine fever virus extensively reorganizes host chromatin architecture and RNA polymerase II activity within hours ...
Researchers have assembled the first chromosome-level reference genome of the endangered Pudong White Pig and uncovered hundreds of breed-specific DNA ...
Researchers have developed ChIPSP, an R package that combines ChIP-seq with Hi-C chromatin loops to identify transcription factor target genes ...
A new method called Spatial-ATAC-Hi-C simultaneously maps chromatin accessibility and three-dimensional genome organization in intact tissue sections, as demonstrated on ...
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© 2025 Scienmag - Science Magazine