RBBP5 Emerges as a Master Epigenetic Switch Controlling the Cell’s 12-Hour Proteostasis Clock
A new PLOS Biology study identifies the COMPASS complex subunit RBBP5 as the central epigenetic regulator of the cell's 12-hour ...
Tag: H3K4me3
Faulty Epigenetic Switch Disrupts Brain Cell Cycles and Drives White Matter Defects in Autism-Linked Disorders
New research shows that pathogenic variants in the chromatin regulator MSL2 disrupt oligodendrocyte precursor cell division and myelination through loss ...
Metabolic Switch in Heart Cells Rewinds Injury Into Regeneration, Study Finds
New research shows that transient inhibition of the mitochondrial enzyme succinate dehydrogenase triggers coordinated metabolic and epigenetic reprogramming across heart ...
Common Antibiotic Calms Children’s Wheezing by Rewriting Inflammatory Memory in Lung Immune Cells
A new study shows azithromycin eases post-inflammatory wheezing in children by inhibiting SETD1B-driven H3K4me3 methylation and rebalancing macrophage polarization in ...
A Single Histone Tag Decides Whether Malaria Parasites Commit to Transmission
Researchers have identified an E2–E3 ubiquitin ligase complex that monoubiquitinates histone H2B to activate the master regulator of sexual commitment ...
Proteasome Gatekeeper RPT2a Controls When Plants Flower by Destroying a Key Histone Protein
New research reveals that the proteasome subunit RPT2a regulates flowering time in Arabidopsis by promoting the degradation of the chromatin ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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