Retrospective blood protein models predict outcomes in 38 HPV16 cancer patients
A retrospective study of 38 patients with advanced HPV16-positive cancers linked baseline and early serum protein measurements to outcomes from ...
Tag: granzyme B
CFH risk variant linked to complement changes in non-AMD eyes
A study links the high-risk CFH Y402H genotype to granzyme B activity, reduced vitronectin and membrane attack complex deposition in ...
Bladder Cancer Protein GSDMB Boosts Immunotherapy by Recruiting Immune Cells
A new study reveals that the protein GSDMB enhances anti-PD-1 immunotherapy in bladder cancer by driving Sema7a-mediated recruitment and activation ...
NK Cell Immunotherapy for Solid Tumors Advances, but Cardiac Safety Questions Remain
A new review maps the rapid rise of NK cell immunotherapy for solid tumors and warns that its cardiovascular safety ...
Common Sweetener Sucralose Shows Surprising Ability to Calm Autoimmune Attacks in Vitiligo
New research shows the artificial sweetener sucralose slows autoimmune depigmentation in mice and suppresses human CD8+ T cell activity by ...
Coumarin Supercharges Natural Killer Cells to Fight Liver Cancer, Study Finds
New preclinical research shows that the plant compound coumarin activates natural killer cells, boosts their mitochondrial energy supply, and shrinks ...
Old Antibiotic Clofoctol Rewires the Immune System to Boost Glioblastoma Immunotherapy
Researchers report that the antibiotic clofoctol redistributes CD8-positive T cells from the bone marrow and enhances their tumor-killing activity, substantially ...
Dissolving Hydrogel Gate Breaks the Debye Screening Barrier in Nanochannel Biosensing
A peptide-DNA hydrogel that disassembles on command allows nanochannel biosensors to overcome Debye screening and track lung cancer immunotherapy responses ...
Engineered NK Cells Target Hidden Cancer Antigen to Control Melanoma in Mice
Brazilian researchers engineered natural killer cells with a TCR-like CAR that recognizes an intracellular melanoma antigen displayed on HLA molecules, ...
Immune Cells That Kill Superbug Bacteria Directly Offer New Hope for Hard-to-Treat Lung Infections
New research in mice shows that IL-17A-producing γδ T cells directly kill Mycobacterium abscessus in the lung, revealing a promising ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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