Genomics Goes Routine: From Model Labs to Honey Bees, Crops and Wild Populations
A new perspective argues that genomics has shifted from a specialized pursuit of well-funded labs to a routine tool now ...
Tag: genome-wide association studies
Children’s education-linked genetic scores differ in ties to mental health within families
A study of 3,223 UK parent-offspring trios finds that cognitive and non-cognitive education-related polygenic scores show different associations with children's ...
Geneticists certify 108 high-confidence Alzheimer’s risk signals
A systematic adjudication framework applied to 29 genome-wide studies produced a catalog of 108 high-confidence genetic signals for Alzheimer's disease ...
Two decades of Mendelian randomization mapped: pleiotropy tops the field’s methodological worries
A bibliometric and content analysis of 21,346 Mendelian randomization publications finds horizontal pleiotropy as the most frequently coded methodological challenge ...
Genome re-identification attack works in theory but falters in practice
A new probabilistic study shows that re-identifying anonymized genomes from predicted traits achieves high precision only under unrealistically favorable assumptions, ...
Rare EGFR mutation sharply raises lung cancer risk in large genetic study
An observational study of 3.3 million research participants found that inherited EGFR T790M was associated with 25-fold higher lung cancer ...
New Genetic Atlas Reveals DNA Changes That Made Humans Vulnerable to Osteoarthritis
When the human genome was first sequenced, one of the most striking findings was how little separates us from our ...
Trans-Ancestry Genetic Risk Score Boosts Heart Disease Prediction in Chinese Adults
A new trans-ancestry polygenic risk score built by fusing East Asian and European genome-wide association data markedly improves coronary artery ...
Massive RNA Dataset Uncovers Hidden Genetic Switches Behind Gene Expression
A large-scale analysis of TOPMed RNA sequencing data shows that most genes are controlled by multiple independent regulatory switches that ...
Africa’s genetic diversity could transform global mental health research
A major new review argues that Africa's unmatched genetic diversity, combined with rising mental health needs and growing continental research ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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