Tag: gene therapy

Researchers report a non-viral, OCT-guided method using gold nanorods and a 980-nm laser to deliver the opsin MCO-020 to targeted ...

A new Oncoscience perspective maps the 2025–2026 glioblastoma clinical trial pipeline across four mechanistic domains, showing how biomarker-guided selection and ...

Infant neuroblastoma is one of the most clinically paradoxical cancers in medicine. Diagnosed during the first year of life, it ...

A sweeping narrative review charts how molecular genetics turned non-malignant blood disorders into the proving ground for modern diagnostics and ...

A new hypothesis proposes that programmable lipid nanoparticles may shape cellular memory systems to extend the durability of mRNA vaccines ...

A comprehensive narrative review from NIH researchers catalogues the clinical trials reshaping dystonia treatment between 2020 and 2025, from novel ...

A McGill University review finds that the ethics of pediatric first-in-human cell and gene therapy trials rests on two foundational ...

A new narrative review outlines how hyaluronidase can transiently open the hyaluronic acid-rich extracellular matrix to enhance nose-to-brain delivery of ...

Researchers established a stable human packaging cell line producing high-titer γ-retroviral vectors pseudotyped with the non-fusogenic BaEV-TR envelope protein, overcoming ...

Researchers used a vector-free CRISPR activation system to boost dopamine biosynthesis genes in cellular models of Parkinsonian neurotoxicity, finding modest ...