Gene Therapy

Credit: CNIO Glioblastomas are the most common and most aggressive brain tumours. Their survival rate has barely increased over the last 50 years, indicating an urgent need to develop new therapeutic strategies. In a paper…

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchangedCredit: Jennifer Cook-Chrysos/Whitehead Institute Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized…

Xue Sherry Gao developing base editors to fix multitude of single mutations that cause diseaseCredit: Jeff Fitlow/Rice University HOUSTON - (April 8, 2021) - Chemical and biomolecular engineer Xue Sherry Gao of Rice University's Brown…

In an article published in the April 8 issue of Nature, the National Institutes of Health's Somatic Cell Gene Editing Consortium provided a detailed update on the progress of their nationwide effort to develop safer and more effective…

KGI assistant professor and UC Berkeley visiting scientist Dr. Kiana Aran has developed this new technology, a CRISPR diagnostics innovation that allows for digitally accurate detection of genetic diseases without amplificationCredit: Keck…

Credit: UVA Health A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent…

FINDINGS A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4…

Toolkit easily incorporates into any laboratory science courseCredit: ChristianaCare St. Georges Technical High School in southern New Castle County, Delaware is the first high school in the United States to use ChristianaCare Gene Editing…

Penn Medicine researchers have found that a mutation-specific RNA therapy improved vision with lasting effects PHILADELPHIA - A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year,…

Joaquin Espinosa, PhD, and his team investigated the role of hypoxia-inducible factors in tumor growth and suppressionCredit: Joaquin Espinosa, PhD A team of University of Colorado School of Medicine researchers recently published a…

Credit: Atsushi Natsume Nagoya University researchers have identified a gene that plays a crucial role in regenerating neurons of African clawed frog tadpoles, which has an unusually high capacity for nerve regeneration. Their study,…

In a new study published in the Cell Research, Chen-Yu Zhang's group at Nanjing University reports "In vivo self-assembled small RNA is the new generation of RNAi therapeutics". The development of RNAi therapy has undergone two major…

Credit: Kim Ratliff, Augusta University The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say. In only the second…

American Association for Cancer Research honors distinguished USC Norris Comprehensive Cancer Center scientistCredit: Keck School of Medicine of USC John D. Carpten, PhD, founding chair for the Department of Translational…

Credit: IGDB Precision genome editing enables the precise modification of DNA in living cells, thus enabling a breadth of opportunities for plant breeding. Prime editors, developed by Prof. David R. Liu and his colleagues, permit…

Novel DLD assay is capable of rapidly assessing host inflammatory response, allowing patients exhibiting a life-threatening hyper-aggressive immune response to be identified and treated expeditiouslyCredit: Singapore-MIT Alliance for…

Credit: Jinan University Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades. A research team led by Dr. Gong Chen, a former professor at Penn…

Join world renowned cancer researchers as they gather to discuss latest advances in cancer cell and gene therapy for solid tumors Alliance for Cancer Gene Therapy wants to change the C-word from Cancer to Cure -- building on the life…

An international collaboration between Great Ormond Street Hospital, the UCL GOS Institute for Child Health and Harvard Medical School has shown that the beneficial effects of gene therapy can be seen decades after the transplanted blood…

The CRISPR-based gene editor, C-to-G Base Editor (CGBE), opens up treatment avenues for up to 40 per cent of genetic disorders caused by single-nucleotide mutationsCredit: Agency for Science, Technology and Research (A*STAR), Genome…