Gene-Activated Matrices Bridge Bone Repair Gap
A new review in Materials Today Bio explores how gene-activated matrices use nanomedicine to sustain bone repair by integrating scaffold ...
Tag: gene therapy
Review details Slack channel mutations in epilepsy
A 2026 review in Acta Epileptologica details how KCNT1 gene mutations alter Slack channel function, leading to various forms of ...
Clinical Trials Show Manageable Long-Term Cardiac Safety for Duchenne Gene Therapy
A pooled analysis of four clinical trials evaluating delandistrogene moxeparvovec in predominantly young, ambulatory patients with Duchenne muscular dystrophy demonstrated ...
Researchers Review Microneedle Technologies for Targeted Gene Therapy and Vaccines
A comprehensive review analyzes how microneedle arrays overcome biological barriers to deliver nucleic acids and gene-editing platforms directly into local ...
Gene Therapy Preserves Vision for Fifteen Months in Retinitis Pigmentosa Mice
A subretinally delivered gene therapy vector incorporating a native untranslated regulatory region achieved fifteen months of sustained structural and functional ...
Overcoming Cellular Barriers: The Clinical Roadmap for Therapeutic CRISPR Gene Delivery
A comprehensive review of sixty-seven studies reveals that biological delivery barriers, rather than editing efficiency, determine the clinical success of ...
Local Immune Modulation and Vector Selection Dictate Gene Therapy Efficacy for Dent Disease
A preclinical study demonstrates that local rapamycin microsphere delivery enables durable lentiviral gene therapy for Dent disease type 1 in ...
Estrogen Steers Stem Cells Toward Bone Through a Newly Mapped Mitochondrial Switch
Researchers report that estradiol activates PDK4 in bone marrow stem cells, which phosphorylates MYH9 to recruit DRP1 and drive the ...
Rubidium chloride ultracentrifugation resolves and quantifies dual-AAV gene therapy vectors
A density gradient equilibrium analytical ultracentrifugation method using rubidium chloride achieved high-resolution separation and accurate quantification of the two highly ...
Long Contact Times on AAV Affinity Resins Reshape Yield and Purity
Extended binding times on AAV affinity resins cause serotype-specific yield losses and VP3 enrichment while sharply improving host-cell impurity clearance ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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