Massive UK Biobank reference panel sharpens genetic imputation worldwide
A new haplotype reference panel built from 490,319 UK Biobank genomes beats the widely used TOPMed r3 panel for most ...
Tag: fine mapping
Scientists Map Regulatory DNA Behind Pig Body Size and Sharpen Genomic Prediction
A study of 1226 Shanxia Long Black pigs integrated fine-mapping, chromatin data, and deep learning to identify functional variants behind ...
Computational Predictions Fail to Match Measured Activity at Prostate Cancer Risk Variants
A re-analysis of prostate cancer reporter assay data shows computational annotations poorly predict measured regulatory activity, while ovarian risk variant ...
Gene Behind Yellow-Green Leaves in Cauliflower Identified and Confirmed by CRISPR
Researchers fine-mapped and functionally validated CauYL, a magnesium chelatase H subunit gene essential for chlorophyll accumulation and normal leaf coloration ...
Fine mapping refines chromosome 3 QTL associated with heat tolerance in maize tassels
Advanced-generation recombinant progenies derived from an F₂ maize population were used to fine-map qMd3, narrowing a chromosome 3 candidate interval ...
Hidden DNA Repeats in the Brain May Shape Splicing and Disease Risk
A large-scale analysis of 336 human prefrontal cortex samples identifies more than 51,000 short tandem repeats linked to alternative splicing ...
A Single Botched Splice May Explain a Deadly Yellow-Leaf Soybean Mutant
Fine mapping of a soybean yellow-leaf lethal mutant has narrowed the cause to a 165-kilobase region on chromosome 10, where ...
Scientists Pinpoint Two Dominant Genes That Shield Wheat From Devastating Spot Blotch
Researchers have identified a novel dominant wheat gene, SbWE35, on chromosome 4BL that, together with the known gene Sb3, controls ...
Wheat Gene Pinpointed in 880-Kilobase Window Offers Durable Defense Against Powdery Mildew
Researchers have fine-mapped a wheat powdery mildew resistance locus to an 880-kilobase interval on chromosome 4B, identified an MLO candidate ...
Scientists Pinpoint a Gene That Switches Off Pollen in Chinese Cabbage
Researchers in Beijing have fine mapped a novel recessive male-sterility gene, Brmy1, in Chinese cabbage and identified the ROS-generating gene ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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