Tag: fibrosis

Single-cell and spatial analyses of human bone marrow reveal that clonal hematopoiesis of indeterminate potential is marked by fibroblast expansion, ...

Proteomic and phosphoproteomic profiling of 149 failing human hearts reveals two molecular subgroups of heart failure that cut across clinical ...

Memorial Sloan Kettering scientists engineered fucoidan-coated nanoparticles that selectively eliminate senescent, P-selectin-positive macrophages driving fibrosis, dissolving scar barriers around tumors ...

A new review maps how organoid and organ-on-a-chip platforms can reconstruct the microenvironmental logic of systemic sclerosis, lupus, and rheumatoid ...

Stanford researchers have published a protocol for a high-throughput stem cell-based screening platform that identifies potential antifibrotic compounds for cardiac ...

A genetically heterogeneous rat study provides the first experimental evidence that maternally inherited mitochondrial haplotype determines the speed at which ...

Long-term treatment with the PKR inhibitor imoxin failed to reduce PKR activation, improve muscle function, or suppress inflammatory and ER ...

A new review argues that reformulating the versatile natural-product drug halofuginone as a hydrochloride salt could tame its toxicity and ...

A comprehensive review shows that microRNA-122 acts as both a master regulator of liver biology and a sensitive, context-dependent biomarker ...

A sweeping new review in Nature Reviews Urology reveals how mechanical forces such as stretch, pressure and shear stress actively ...