Fibrosis Marker HE4 Predicts Death and Heart Attacks a Decade Out in Coronary Patients
A new ten-year study of nearly 400 angiographically confirmed coronary artery disease patients shows that the profibrotic protein HE4 independently ...
Tag: fibrosis
Engineered Macrophages Emerge as a New Frontier in Cell Therapy for Solid Tumors
A new review details how chimeric antigen receptor-engineered macrophages are overcoming the barriers that stalled CAR-T therapy in solid tumors, ...
Endurance Exercise Reshapes the Liver in Males and Females Through Distinct Molecular Routes
New research from the University of Missouri shows that endurance exercise improves liver health in both sexes but rewires the ...
Immune Cell Traps and a Lipid Messenger Drive Scarring in Endometriosis
New research reveals that neutrophil extracellular traps and the lipid messenger sphingosine 1-phosphate form a self-amplifying feedback loop that drives ...
Hedgehog-Responsive Perivascular Cells Emerge as Master Switches of Blood Vessel Repair and Disease
A new review synthesizes a decade of evidence showing that GLI1-positive perivascular cells act as state-dependent regulators of angiogenesis, capable ...
Feverfew Compound Parthenolide Eases Skin Fibrosis by Stabilizing Mitochondria-ER Contacts
A new study shows that parthenolide, a compound from feverfew, alleviates cellular senescence and skin fibrosis in localized scleroderma by ...
Aging Muscle Fails Through Broken Cell-to-Cell Communication, Review Finds
A new review in Aging Cell argues that skeletal muscle aging is driven by the breakdown of multicellular communication networks ...
Plant Compounds Show Promise in Taming Radiation-Induced Fibrosis Through TGF-β Control
A new review details how plant-derived compounds such as curcumin, resveratrol, and EGCG modulate TGF-β signaling to potentially limit radiation-induced ...
Single-Cell Atlas Reveals Macrophages That May Drive Chronic Kidney Transplant Rejection
A single-cell multi-omic study of transplanted mouse kidneys identifies SPP1-positive macrophages and a CEBPβ-centered regulatory program as candidate drivers of ...
Epigenetic Enzymes Emerge as Promising Drug Targets for Endometriosis
A new review in Reproductive Sciences details how dysregulated histone deacetylases drive endometriosis and how existing and experimental HDAC inhibitors ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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