Scientists Uncover Hidden Protein Driver Behind Scarring Kidney Disease
New research reveals that the protein Annexin A1 drives kidney fibrosis by activating YAP signaling and suppressing autophagy in renal ...
Tag: fibroblast activation
The Hidden Architects of Colorectal Cancer: How Fibroblasts Drive Treatment Failure
A new review in Cancer Cell International details how cancer-associated fibroblasts remodel the colorectal tumor microenvironment and drive resistance to ...
Endothelial Angptl2 Emerges as Central Driver of Influenza-Linked Lung Fibrosis
New research identifies endothelial Angptl2 as a key molecular driver linking influenza-induced vascular injury to pulmonary fibrosis through EndMT and ...
Hidden RNA Switch Drives Deadly Scarring of the Lungs, Study Finds
Researchers have identified an RNA-based molecular circuit involving H19, miR-103a-3p and TRIOBP that drives the scar-forming transformation of lung cells ...
Macrophage Exosomes Carry a MicroRNA That Drives Scarring in the Lung, Study Finds
Researchers report that M2 macrophage-derived exosomal miR-350-5p accelerates pulmonary fibrosis by suppressing Smad7 and amplifying TGF-beta signaling in lung fibroblasts ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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