Blood-based DNA methylation patterns track breast cancer response to chemotherapy
A new study links methylation changes in the KDM5 gene family and cofactors, measured in blood before and after neoadjuvant ...
Tag: EZH2
Metabolic Enzyme NNMT Drives Ovarian Hormone Disorder Through Epigenetic Rewiring
New research in Nature Metabolism reveals that the metabolic enzyme NNMT drives hyperandrogenism in polyendocrine metabolic ovarian syndrome by depleting ...
New Molecular Targets Are Reshaping Personalized Treatment of Low-Grade Non-Hodgkin Lymphoma
A new Research Topic in Frontiers in Hematology highlights epigenetic targets, immunotherapy combinations, resistance mechanisms, and prognostic models driving personalized ...
USP7: The Double-Edged Deubiquitinase That Tumors Cannot Live Without
A new review in Cancer Cell International maps how the deubiquitinase USP7 acts as both tumor promoter and suppressor depending ...
Epigenetic Drug Valemetostat Shows Dual Action Against HTLV-1 Eye Inflammation
A new study shows that the dual EZH1/2 inhibitor valemetostat counteracts HTLV-1-induced epigenetic changes in retinal cells and suppresses viral ...
Tiny Stem Cell Vesicles Loaded with miR-124 Strike Dual Targets to Curb Colorectal Cancer
Scientists engineered stem cell-derived vesicles to deliver tumor-suppressive miR-124 into colorectal cancer cells, silencing EZH2, weakening STAT3 signaling, and shrinking ...
Zebrafish Reveal How Polycomb Complexes Sculpt the Heart and Fins
A new review shows that Polycomb repressive complexes PRC1 and PRC2 are essential for zebrafish heart looping, contraction and pectoral ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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