Migrasomal miRNA reduces bone loss in mouse osteoporosis model
Pre-osteoblast-derived migrasomes delivered miR-21a-5p to inhibit osteoclast differentiation in cell assays and reduced bone loss in an ovariectomy mouse model.
Tag: extracellular vesicles
Review links microglial metabolism to adult neurogenesis regulation
A 2026 mini review concludes that microglial metabolic states may connect brain pathology with adult neurogenic niche remodeling through phagocytosis, ...
miR-142-3p suppresses tumors but can reshape their surroundings
A 2026 review finds that miR-142-3p generally suppresses tumor-cell growth and improves drug response inside cancer cells, while its extracellular-vesicle ...
Kidney transplant electrolyte disorders do not track NCC activation
Two human cohorts found that about 24% of calcineurin-inhibitor-treated kidney transplant recipients had a pseudohypoaldosteronism-like triad, but no corresponding increase ...
Extracellular Vesicles Could Map the Location of Metastatic Cancer
A proposed liquid-biopsy strategy combines tumor-associated and organ-associated markers on circulating extracellular vesicles to infer metastatic sites, but it remains ...
Narrative review evaluates vesicle microRNAs as HSV-1 uveitis biomarkers
A narrative review identifies aqueous-humor extracellular-vesicle microRNAs as promising but unvalidated candidates for characterizing the local intraocular environment in HSV-1 ...
Stage-aware non-coding RNA panels emerge as diabetic retinopathy biomarker framework
A structured review finds that microRNAs provide the strongest evidence for stage-associated diabetic retinopathy biomarkers, but adjacent-stage validation and longitudinal ...
High-altitude exposure linked to α-synuclein burden and mouse pathology
A multi-method study linked chronic high-altitude exposure to elevated α-synuclein levels and worse pathology in a mouse model, while human ...
Research report: Editorial: Development of novel engineered biomaterials with clinical translation prospects for chronic disease theranostics
A 2026 editorial describes preclinical and review evidence on lung scaffolds, conductive diabetic-wound hydrogels, extracellular vesicles and liver-targeted nanoparticles while ...
Systematic review finds limited direct evidence of macrophage environmental memory
A systematic review of 119 studies found that only four directly demonstrated persistence or altered recall in macrophages or monocytes ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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