The Ovary Never Retires: Scientists Discover It Keeps Remodeling Itself for Decades After Menopause
A proteomic study of 28 healthy ovaries from women aged 50 to 75 reveals that the organ undergoes progressive molecular ...
Tag: extracellular matrix
Hydrogels That Heal: How ECM-Mimicking Biomaterials Are Rewriting Regenerative Medicine
The appeal of hydrogels in regenerative medicine begins with a deceptively simple physical observation: soft tissues of the human body ...
Hidden Nanovesicles in Decellularized Pericardium Trigger New Blood Vessel Growth
Nanovesicles embedded in decellularized bovine pericardium drive blood vessel formation in cell cultures and rescue ischemic limbs in mice, opening ...
Immune Cells Remodel Skin Architecture in Post-Kala-Azar Dermal Leishmaniasis
New research reveals how chemokine-driven immune infiltration and inflammatory enzymes dismantle the skin's structural framework in Post-Kala-Azar Dermal Leishmaniasis, explaining ...
Mechanical Stress Hotspots Guide Where Muscle Cells Fuse, Study Finds
Researchers at the Max-Planck-Zentrum für Physik und Medizin show that mechanical stress hotspots and extracellular matrix memory guide where muscle ...
Tiny Membrane Bubbles May Explain How Glaucoma Damages the Optic Nerve
New research shows that Caveolin-1, the core protein of mechanosensitive caveolae, is concentrated in optic nerve head astrocytes and rises ...
Stable Vitamin C Derivative Calms Inflammation and Boosts Collagen in Human Lung Cells
A stable vitamin C derivative reduced pro-inflammatory cytokines and increased collagen and hyaluronan synthase levels in human lung fibroblasts in ...
Enzyme That Softens Tissue Barriers Could Open the Nose-to-Brain Route for Gene Therapy
A new narrative review outlines how hyaluronidase can transiently open the hyaluronic acid-rich extracellular matrix to enhance nose-to-brain delivery of ...
3D Tumor Models Expose How Biliary Tract Cancers Evade Chemotherapy
A new review argues that three-dimensional tumor models, including patient-derived organoids, can reveal the drug resistance and apoptosis evasion mechanisms ...
Scaffold Protein LAMB1 Drives Esophageal Cancer Growth Through JAK2/STAT3 Pathway
New research shows that the extracellular matrix protein LAMB1 accelerates esophageal squamous cell carcinoma by activating JAK2/STAT3 signaling, suggesting it ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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