Tag: extracellular matrix

A new review in Nature Reviews Clinical Oncology details how the tumour extracellular matrix, or matrisome, drives cancer progression and ...

Deleting the RNA splicing factor PTBP1 in cardiac fibroblasts reshapes the profibrotic response by altering alternative splicing of key fibrosis-related ...

Researchers show that Myxococcus xanthus switches between swarming and rippling through just two mechanisms—local cellular alignment and congestion-triggered reversals.

A new review proposes a staged, evidence-bound framework combining patient-specific iPSCs, atrial microphysiological systems and nanomedicine to model and potentially ...

A new imaging mass cytometry pipeline reveals region-specific extracellular matrix environments that shape immune cell behaviour during allergic airway inflammation ...

Deleting the fish-specific actinodin genes flips collagen fiber orientation in zebrafish fins from parallel to perpendicular, reshaping the appendage into ...

A new glycoproteomic analysis shows that protein-residual N-glycosylation of extracellular matrix proteins marks a myCAF-enriched stromal state in pancreatic ductal ...

New research shows that cerebrospinal fluid TIMP2 levels rise with age and track neurodegeneration in Parkinson's disease, while TIMP2 gene ...

A new study reveals that the epigenetic enzyme DOT1L protects cartilage in osteoarthritis by boosting ITCH expression, which in turn ...

A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...