Tumor Cells Build Their Own Blood Vessels in Colorectal Cancer, Review Finds
A new review in Cell Division details how colorectal cancer cells form their own blood-supply channels through vasculogenic mimicry, a ...
Tag: extracellular matrix remodeling
Neutrophils May Act as Dormancy Releasers for Lung Metastasis, Review Finds
A new review in Biological Procedures Online describes how activated neutrophils, through NETs and inflammatory mediators, may disrupt dormancy niches ...
Cancer-associated fibroblasts rewire tumor metabolism to block immunotherapy
A new review details how metabolically reprogrammed cancer-associated fibroblasts build immune-excluded and immunosuppressive tumor niches that undermine checkpoint blockade, and ...
Quercetin reduces acute inflammatory and matrix-remodeling markers in mouse intracerebral hemorrhage
An experimental study found that quercetin reduced selected inflammatory and extracellular matrix-remodeling markers 24 hours after mouse intracerebral hemorrhage, while ...
Scientists Map the Hidden Cellular Wiring That Drives Rheumatoid Arthritis Joint Destruction
A cross-species single-cell and spatial transcriptomics study reveals a conserved Notch/AP-1 to fibronectin and thrombospondin signaling axis operating in a ...
Gardenia-Derived Genipin Emerges as a Therapeutic Candidate for Peripheral Nerve Diseases
A new perspective proposes that the gardenia-derived compound genipin exerts its therapeutic effects in peripheral nerve diseases primarily through crosslinking ...
Frozen Shoulder Study Points to Scar Tissue Remodeling, Not Cell-Death Programs
A three-cohort transcriptomic reanalysis finds extracellular-matrix remodeling as the most reproducible molecular signature of frozen shoulder, while pyroptosis, ferroptosis, and ...
SRPX2 Emerges as a Master Switch Behind Colorectal Cancer Spread and Immune Evasion
New research identifies the secreted protein SRPX2 as a molecular switch that stabilizes the TGF-beta receptor to drive metastasis and ...
Rare Gene Mutation Rewires Developmental Programs in Alazami Syndrome, Revealing Cardiac Risk
In a finding that could reshape how clinicians think about one of the rarest neurodevelopmental disorders on record, a team ...
Sepsis May Leave Tissues Primed for Cancer, Review Argues
A new review in the Journal of Translational Medicine argues that sepsis may remodel tissues through an Immuno–Vascular–Matrix Triad in ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!