Korean Cohort Links Homocysteine to Imprinted Methylation Domains
Researchers conducted an epigenome-wide association study (EWAS) of fasting plasma homocysteine in a large Korean cohort, identifying three imprinted genomic ...
Tag: EWAS
Asian-led epigenome study uncovers new DNA methylation markers of artery wall thickness
An EWAS in a Singapore-based Asian cohort identified three novel DNA methylation markers for carotid intima-media thickness and linked one ...
Blood lipid–linked DNA methylation patterns replicate in Korean adults and tie to epigenetic aging
An epigenome-wide study of 1,527 Korean adults confirms core lipid–methylation loci and links ABCG1 methylation to the association between accelerated ...
Benchmarking Study Reveals Best Statistical Tools for Detecting Variable DNA Methylation
A comprehensive simulation-based evaluation of eight computational models finds that the joint location-and-scale score test JLSsc delivers the most reliable ...
Chemical Tags on Brain DNA Reveal How Alzheimer’s Risk Genes Do Their Damage
A large postmortem study identified 107 brain DNA methylation sites linked to Alzheimer's pathology and showed that methylation partially mediates ...
Hidden Flaws in a Leading DNA Methylation Chip Could Skew Studies of Diverse Populations
A comprehensive audit of the Illumina EPIC methylation array reveals tens of thousands of probes with cross-hybridization, misannotation, or population-specific ...
Blood DNA Methylation Across Pregnancy Offers New Clues to Preeclampsia Risk
A longitudinal epigenome-wide study tracked DNA methylation in maternal blood across all three trimesters, identifying nine differentially methylated regions associated ...
New DNA Methylation Chip Passes Its Biggest Test Yet, With Surprises for Cancer Research
A comprehensive independent evaluation finds the new Illumina MethylationEPIC v2 BeadChip offers expanded enhancer coverage, low-input performance down to one ...
Machine Learning Maps the Exploding World of Epigenetic Epidemiology Research
Researchers at the CDC and Emory University have built a machine learning-powered database that automatically curates the rapidly growing literature ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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