Tag: epithelial-mesenchymal transition

A new review explains how tumor cells reversibly switch identities through epigenetic and microenvironmental programs, driving metastasis and therapy resistance.

A new study integrates single-cell transcriptomics with human tissue and mouse model validation to show that TGF-beta/Smad-driven dialogue between epithelial ...

Researchers at Harbin Medical University report that the RNA-binding protein PTBP3 stabilizes SMAD3 mRNA and drives podocyte epithelial-to-mesenchymal transition, and ...

A new review in the Journal of Translational Medicine maps how perineural invasion may drive hepatocellular carcinoma aggression, organizing the ...

Researchers have identified a LAPTM5-WWP2-OPTN mitophagy cascade that drives retinal pigment epithelium senescence and subretinal fibrosis through cGAS-STING activation, with ...

A new review in Cancer Cell International details how cancer-associated fibroblasts remodel the colorectal tumor microenvironment and drive resistance to ...

A large-scale proteomic study of 404 cervical cancer samples has revealed three molecular subtypes of squamous cell carcinoma with distinct ...

New research reveals that neutrophil extracellular traps and the lipid messenger sphingosine 1-phosphate form a self-amplifying feedback loop that drives ...

Researchers report that M2 macrophage-derived exosomal miR-350-5p accelerates pulmonary fibrosis by suppressing Smad7 and amplifying TGF-beta signaling in lung fibroblasts ...

New research shows that the milk protein gene CSN3 is elevated in colorectal cancer and drives tumor growth, invasion, and ...