Hidden Aggression: Machine Learning Exposes Dangerous Biology in Low-Risk Prostate Cancer
Researchers at KTH Royal Institute of Technology used multi-omics analysis and machine learning to uncover molecular features linked to aggressive ...
Tag: epigenomics
DNA Methylation Episignatures Emerge as a Powerful New Diagnostic Layer for Rare Disease
A new review explains how DNA methylation episignatures provide functional evidence of disease mechanism in rare genetic disorders, helping resolve ...
Deep Learning Tool Reads Leukemia’s Regulatory Code to Predict Patient Risk
A new deep learning framework called TERfinder integrates multi-omics data to map enhancer-promoter interactions in myeloid leukemia, pinpointing key regulatory ...
Pig DNA Methylation Map Reveals Hidden Genetic Switches Behind Meat Traits
A massive multi-omics atlas of pig skeletal muscle shows how genetically regulated DNA methylation links sequence variation to gene expression ...
Hidden Flaws in a Leading DNA Methylation Chip Could Skew Studies of Diverse Populations
A comprehensive audit of the Illumina EPIC methylation array reveals tens of thousands of probes with cross-hybridization, misannotation, or population-specific ...
Spatial Multi-Omics Needs Reproducibility Standards Before It Can Reach the Clinic
A new review argues that spatial multi-omics must overcome reproducibility and standardization gaps before the technology can deliver on precision ...
Duck Genome Study Reveals Master Genetic Switch Behind Fat Deposition
A multi-omics study in ducks has uncovered a selected distal enhancer that remotely controls the ADM gene through SMAD2 recruitment, ...
Lost DNA Fragment Weakens the Inheritance of Methylation Patterns in Plants
Two independent studies converge on a 2.7 kilobase DNA deletion that reduces the fidelity of methylation inheritance in plants, suggesting ...
Light-Patterned DNA Tags Give Single-Cell Sequencing a Sense of Place
A new light-based barcoding technique called scSTAMP-seq stamps spatial coordinates onto individual cells using photocleavable DNA tags, enabling joint transcriptomic ...
Chemical Tag on Histones Governs Rice Immunity Against Viruses and Insect Pests
A new Genome Biology study shows that lysine succinylation of histones regulates rice defense genes, and that disabling the desuccinylase ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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