Epigenetic Switches Could Arm Rice Against Its Deadliest Pathogens
A comprehensive review reveals how DNA methylation, histone modifications and non-coding RNAs regulate rice immunity and could enable epigenetic breeding ...
Tag: epigenetics
Lung Immune Cells Show Lasting Epigenetic Changes in Long COVID Patients
A Swedish longitudinal study finds that lung immune cells, but not blood cells, undergo lasting DNA methylation changes in long ...
Epigenetic Switch That Shields Cartilage From Osteoarthritis Is Revealed
A new study reveals that the epigenetic enzyme DOT1L protects cartilage in osteoarthritis by boosting ITCH expression, which in turn ...
Cancer Reshapes the SUMOylation Landscape to Sabotage Muscle Function, Study Finds
New research reveals that cancer reorganizes the SUMOylation landscape in skeletal muscle and alters L3mbtl2-mediated transcriptional control, offering a molecular ...
Cohesin Builds Molecular Fences That Keep Active Genome Domains From Mixing
New research shows that the cohesin complex acts as a molecular barrier in living human cells, preventing condensed euchromatic domains ...
Single-Cell Multi-Omics Reveals How Cancer Clones Evolve Genotype and Phenotype Together
A Nature Reviews Cancer review explains how genotype-aware single-cell multi-omics and phylogenetic reconstruction are revealing how mutant clones in healthy ...
KIF11 Inhibition Rewires Prostate Cancer Cell Identity to Restore Sensitivity to Antiandrogen Drugs
Low-dose inhibition of the motor protein KIF11 rebuilds enhancer–promoter loops at the androgen receptor locus, restoring drug sensitivity in otherwise ...
Environmental Stress May Have Loosened DNA Repair Rules on the Y Chromosome
A new hypothesis proposes that prolonged environmental stress in the ancient southern Levant transiently relaxed DNA repair constraints in one ...
CRISPR Methylation Editing Rewrites the Cancer Epigenome Toward Causation
A new review argues that CRISPR-based DNA methylation editing can transform cancer epigenetics from a correlative science into a causal ...
Chromatin Regulator ANKRD11 Emerges as Switch That Reinvigorates Exhausted T Cells
Researchers have identified ANKRD11 as a chromatin regulator whose loss reprograms CD8+ T cells to fight chronic hepatitis B and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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