Epigenetic Enzymes Emerge as Promising Drug Targets for Endometriosis
A new review in Reproductive Sciences details how dysregulated histone deacetylases drive endometriosis and how existing and experimental HDAC inhibitors ...
Tag: epigenetics
Airborne Benzene Linked to Fatty Liver Disease Through Faster Biological Aging
A UK Biobank study of more than 400,000 adults finds that long-term low-level benzene exposure raises the risk of non-alcoholic ...
Enhancers That Free Stalled Polymerase Drive Tumor-Feeding Macrophages Across Cancers
A pan-cancer single-cell epigenetic study reveals that tumor-supportive macrophages arise through distinct enhancer-driven trajectories in which releasing paused RNA polymerase ...
Hidden RNA Codes: How Splicing and Non-Coding RNAs Help Plants Survive Stress
A new review synthesizes evidence that alternative splicing and long non-coding RNAs form an integrated RNA regulatory network that underpins ...
RNA Chemical Tag METTL3 Found Essential for Building the Newborn Uterus
A new study shows that the RNA-modifying enzyme METTL3 and its m6A marks are essential for the postnatal specification of ...
Virtue in the Middle: Epigenetics Scholars Reject Nature-Nurture Dichotomies
Epigenetics researchers Luca Chiapperino and Francesco Paneni argue that the field's future lies between reductionism and holism, rejecting both nature-nurture ...
New DNA Methylation Chip Passes Its Biggest Test Yet, With Surprises for Cancer Research
A comprehensive independent evaluation finds the new Illumina MethylationEPIC v2 BeadChip offers expanded enhancer coverage, low-input performance down to one ...
Chromatin Remodeler INO80 Emerges as Master Gatekeeper of Lymphatic Vessel Development
A new study identifies the chromatin remodeler INO80 as a critical regulator of ETS transcription factor programs required for embryonic ...
Genetic Switches for DNA Methylation Mapped Across the Colon Cancer Genome
A genome-wide study of 250 colon cancer patients has mapped nearly 50 million genetic associations with DNA methylation at single-base ...
Silenced Gene Accelerates Heart Failure After Heart Attack, Study Finds
Researchers have discovered that epigenetic silencing of the FCGR2A gene by promoter hypermethylation, driven by the transcription factor ATF3, worsens ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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